1.  to pin down;  to hold down;  to press down
also written as 圧さえる
2.  to cover (esp. a part of one's body with one's hand);  to clutch (a body part in pain);  to press (a body part)
3.  to get a hold of;  to obtain;  to seize;  to catch;  to arrest
4.  to grasp (a point);  to comprehend
5.  to quell;  to subdue;  to suppress;  to repress;  to hold back;  to check;  to curb;  to contain