1. to hold (an event); to give (a dinner, party, etc.)
何度か自宅でパーティーを催しています。I have held parties at home several times.
2. to feel (sensation, emotion, call of nature, etc.); to show signs of
彼は催したんでトイレに行ってくるって。He says he has to go, so he's heading to the bathroom.