going up and down;  ascent and descent;  climb and descent
 going downstream (in a boat)
 downhill road;  descending road
 downhill grade;  downgrade
 down-train;  train heading toward the ending point of its route
 travelling east (esp. to Edo) from Kyoto
 products originating in Kansai (Edo period)
 loose bowels;  diarrhea;  diarrhoea
 down train;  outbound train
 downstream transmission speed