1.  going down;  fall;  decrease;  drop
2.  knocking down (in boxing);  flooring;  being knocked down;  being floored
3.  being out of action (due to illness, exhaustion, etc.);  being down (e.g. with a cold);  being knocked out (from alcohol);  being out of it;  collapsing
4.  going down (of a computer system, server, etc.);  crashing
5.  (number of) outs
6.  being down (in points, games, etc.);  behind behind;  trailing
7.  down (American football)
8.  down (feathers)