setback;  failure (e.g. plans, business);  frustration;  discouragement
 to be disheartened;  to lose heart;  to be sprained;  to be snapped;  to be broken
 to sprain;  to twist;  to dampen (enthusiasm);  to discourage;  to dishearten
 setback;  deadlock;  standstill;  impasse;  miscarriage
 to spoil someone's start;  to kill someone's enthusiasm;  to take the wind out of someone's sails
 feeling of frustration;  sense of failure
 to spoil someone's start;  to kill someone's enthusiasm;  to take the wind out of someone's sails
 sprain;  wrench;  bruise;  contusion;  fracture
 spraining of a bone joint
 to spoil someone's start;  to kill someone's enthusiasm;  to take the wind out of someone's sails
 to spoil someone's start;  to kill someone's enthusiasm;  to take the wind out of someone's sails